Centuries: 14th century - 15th century - 16th century
- May 20 - Portuguese explorer Vasco da Gama arrives at Calicut (now Kozhikode), India
- July 31 - On his third voyage to the Western Hemisphere, Christopher Columbus becomes the first European to discover the island of Trinidad.
- Girolamo Savonarola, ruler of Florence, is executed for criticizing the Pope.
- Christopher Columbus lands on the South American continent.