Centuries: 15th century - 16th century - 17th century
- The first official translation of the entire Bible in Swedish
- February 12 - Pedro de Valdivia founds Santiago de Chile.
- May 8 - Hernando de Soto reaches the Mississippi River naming it Rio de Espiritu Santo.
- May 23 - Jacques Cartier departs Saint-Malo France on his third voyage.
- Muslims seal off The Golden Gate in Jerusalem.