Centuries: 4th century BC - 3rd century BC - 2nd century BC
- October/November - Pharaoh Ptolemy IV of Egypt marries his sister, who rises to the throne as Arsinoe III of Egypt.
- Eratosthenes measures the size of the Earth.
- On the island Crete, the Gortynians occupy Matala.
- The Romans begin work on the Via Flaminia, a road leading north out of the city.