Centuries: 3rd century - 4th century - 5th century
- The Council of Laodicea is held.
- Eunomius of Cyzicus becomes Bishop of Cyzicus.
- Macedonius I is deposed as Patriarch of Constantinople and replaced with Eudoxius of Antioch.
- Meletius becomes Patriarch of Antioch.
- St. Jerome is baptized in Rome (possible date).
- Sextus Aurelius Victor becomes prefect of Pannonia.
- Saint Ninian, missionary in Scotland (approximate date)
- Pelagius, British monk (approximate date)
- Saint Mesrob, Armenian monk
- Eustathius of Antioch (possible date)\n