The Bronx High School of Science is a public high school in the Bronx, New York City. Founded in the 1930's with a traditional focus on mathematics and science, "Bronx Science," as the school is known, is one of a triumvirate of elite public schools in New York City, together with Stuyvesant High School (in Manhattan) and Brooklyn Technical High School. Admission to the three schools is by competitive examination only, and only residents of the five boroughs of the City of New York are eligible to attend. The school is a perennial leader in the Intel/Westinghouse science competition.

Bronx Science counts several Nobel Prize winners among its graduates, including Dr. Jonas Salk (inventor of the polio vaccine). Other noted graduates include actors Jon Favreau and James Wood and chess grandmaster Arthur Bisguier.

The current Principal is Valorie Reidy.