Cathedral Parish (大堂區 Pinyin: Dà Tángqū; Portuguese: Freguesia da Se) is a southeast region of Macau Peninsula, Macau, the People's Republic of China. It is the second largest peninsular Macanese district (after Our Lady Fatima Parish).

Its western part is the historic financial centre of Macau. Praia Grande Central Business District Business District (南灣中心商業區) is in south-central part of the district. All of the Macanese banks (over 20) have offices here.

Quality restaurants, 4-star and 5-star hotels are mostly located in this district. High-rise buildings are located on the eastern part, which was reclaimed from sea. And the eastern edge is the Hong Kong-Macau Ferry.