The Convention on Psychotropic Substances was adopted in 1971 under the auspices of the United Nations. It was adopted to supplement the Single Convention on Narcotic Drugs. While the Single Convention applied primarily to opium and opium-derivatives (morphine, heroin, etc.), this Convention applied to other drugs with mental effects, such as LSD. It requires its parties to criminalize the use, possession or manufacture of drugs referred to in its schedule, which can be updated.

Provisions to prevent the international trafficking of drugs covered by this Convention are contained in the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.