EgyptAir Flight 648 was a Boeing 737 aircraft on a flight from Athens to Cairo, carrying 96 people. On November 23, 1985, three men of the Abu Nidal terrorist group hijacked the aircraft over the Mediterranean. An Egyptian sky marshal shot one of the hijackers, setting off a gunfight that depressurized the aircraft and forced it to land in Valletta, Malta.

On the ground in Malta, the hijackers demanded fuel. When they did not get it, they shot two American and three Israeli passengers, three of whom miraculously survived.

After hours of negotiations, Egyptian commandos stormed the aircraft by using an explosive device that killed many passengers. The commandos boarded the aircraft and fought with the hijackers, who threw several hand grenades inside the cabin. The explosions and fire severely damaged the aircraft. 58 passengers died, as well as two of the six crew members.

Until September 11, 2001, this was the deadliest airplane hijacking in history.