Uzbekistan joined the Commonwealth of Independent States in December 1991. However, it is opposed to reintegration and withdrew from the CIS collective security arrangement in 1999. Since that time, Uzbekistan has participated in the CIS peacekeeping force in Tajikistan and in UN-organized groups to help resolve the Tajik and Afghan conflicts, both of which it sees as posing threats to its own stability. Uzbekistan is an active supporter of U.S. efforts against worldwide terrorism and joined the coalitions which have dealt with both Afghanistan and Iraq. It is a member of the United Nations, the Euro-Atlantic Partnership Council, Partnership for Peace, and the Organization on Security and Cooperation in Europe (OSCE). It belongs to the Organization of the Islamic Conference (OIC) and the Economic Cooperation Organization--comprised of the five Central Asian countries, Azerbaijan, Turkey, Iran, Afghanistan, and Pakistan. It is a founding member of and remains involved in the Central Asian Union, formed with Kazakhstan and Kyrgyzstan, joined in March 1998 by Tajikistan.

Disputes - international: none

Illicit drugs: limited illicit cultivation of cannabis and very small amounts of opium poppy, mostly for domestic consumption, almost entirely eradicated by an effective government eradication program; increasingly used as transshipment point for illicit drugs from Afghanistan to Russia and Western Europe and for acetic anhydride destined for Afghanistan