Francis Lightfoot Lee (October 14, 1734 - January 11, 1797), was a signer of the United States Declaration of Independence as a representative of Virginia.
He was educated at home. In 1758 he was elected to the Virginia House of Burgesses, where he served until 1775. He was a radical patriot, siding with Patrick Henry in opposing the Stamp Act. He called for a general congress and a Virginia Convention in 1774, which he attended. He was a delegate to the first Continental Congress, serving until 1779. He was a member of the Virginia Senate before his retirement.