Lymph nodes are components of the lymphatic system. Clusters of lymph nodes are found in the underarms, groin, neck, chest, and abdomen. Lymph nodes act as filters, with an internal honeycomb of connective tissue filled with lymphocytes that collect and destroy bacteria and viruses. When the body is fighting an infection, these lymphocytes multiply rapidly and produce a characteristic swelling of the lymph nodes.

The spleen and tonsils are large, well-known lymph nodes.