Manzai (漫才) is a style of stand-up comedy in Japan, where two performers—a straight man (tsukkomi) and a funny man (boke)—trade jokes at great speed. Most of the jokes revolve around mutual misunderstandings, double-talk, puns and other verbal gags.

The form is associated with the Osaka region, and manzai performers often speak in the Kansai dialect. The most famous manzai company is Osaka's Yoshimoto Kogyo.

Kitano Takeshi, now a famous actor and director, was originally a manzai comedian.