The mucocutaneous boundary is the point near the orifices of the body at which the external skin stops and the mucosa that covers the inside of the body starts.

A mucocutaneous boundary is found at the lips, at the tip of the foreskin and similar locations. The mucocutaneous boundary is highly erogenous tissue. Winkelmann reports the mucocutaneous boundary is a "specific erogenous zone with rete ridges where the nerve endings rise closer to the surface. The ridged band area of the prepuce is one such example.

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