PIC may stand for:
- PIC microcontroller
- Picture
- Pacific Islanders in Communications
- Pacific Islands Club
- Parallel interference cancellation
- Parent Indicator Code (US military)
- Particle-in-cell
- Particulate inorganic carbon
- Partners in Crime (band)
- Patrol in Council (Scouts)
- Peripheral Imaging Corporation
- Peripheral inserted catheter
- Peripheral interface controller
- Peripheral intravenous catheter
- Person in charge
- Personal identification card
- Personal identification code
- Personal information carrier
- Personal information collection
- Personal Information Communicator
- Personal interactive communicator
- Personnel Investigations Center (US govt)
- Photographic Interpretation Center (several US)
- Photographic Interpretation Centre (UK)
- Photonic integrated circuit
- Pilot in command (aviation)
- Pitch-In Canada
- Plastic insulated cable
- Plastic insulated conductor
- Plume impingement contamination
- Pocket ion chamber
- Polyisocyanurate
- Port interface card
- Portable intensive care
- Position independent code (computers)
- Potential impact circle
- Predesignated Interexchange Carrier
- Primary Interexchange Carrier