Power Macintosh, or Power Mac, is the name of a line of Apple Macintosh personal computer based on a PowerPC processor. Apple Computer started producing Power Macs in 1994; earlier models were based on Motorola 68000 processors, and the MacOS operating system released with the new machines included an emulator to enable programs written for the older machines to run without changes.

Other PowerPC-based Macintosh lines include the iMac, iBook, and various PowerBook models since 1995.

The earliest Power Macs were PowerPC 60x processor-based, followed by the G3, the G4, and recently the G5. Many have dual processor configurations.

See also list of Macintosh models grouped by CPU