Samuel Musgrave (September 29, 1732 - July 5, 1780) was an English classical scholar and physician.

Musgrave was born at Washfield in Devon, and was educated at the University of Oxford. There he was elected to a Radcliffe travelling fellowship, he spent several years abroad. In 1766 he settled at Exeter, but not meeting with professional success moved to Plymouth. He ruined his prospects, however, by the publication of a pamphlet in the form of an address to the people of Devon, accusing certain members of the British government of having been bribed by the French government to conclude the peace of 1763, and declared that the Chevalier d'Eon de Beaumont, French minister plenipotentiary to England, had in his possession documents which would prove the truth of his assertion. De Beaumont repudiated all knowledge of any such transaction and of Musgrave himself, and the House of Commons in 1770 decided that the charge was unsubstantiated. Thus discredited, Musgrave gained a precarious living in London by his pen until his death, in reduced circumstances, on the 5th of July 1780. He wrote several medical works, now forgotten; and his edition of Euripides (1778) was a considerable advance on that of Joshua Barnes.

See W Munk, Roll of the Royal College of Physicians, ii. (1878).

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