Shin-Osaka Station (新大阪駅), or New Osaka Station, is a train station in Yodogawa Ward, Osaka, Japan. It is the western terminus of the Tokaido Shinkansen, and the eastern terminus of the Sanyo Shinkansen.

Shin-Osaka is not to be confused with Osaka Station, which is located closer to the center of the city (about 3 km to the south). The new station was built in 1964 to avoid the engineering difficulties of running Shinkansen lines into the center of the city. The Kyoto and Midosuji lines provide convenient connections to other stations around the city center.

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