Theophanu (956 - 991) (also known as Theophano) was born in Constantinople, the daughter of the Byzantine Emperor Romanus II and Theophanu. In 972 Theophanu married Otto II of Saxony, emperor of the Holy Roman Empire, to seal a treaty between the Byzantine Empire and the Holy Roman Empire.
Their children were:
- Sophia, Abbess of Gandersheim, born 978
- Adelaide, Abbess of Quedlinburg, born 977
- Matilda of Saxony, born 978, and
- Otto III, Holy Roman Emperor, born 980