Thisbe is the fair maiden in the Roman fable of Pyramus and Thisbe, where she in a forbidden relationship with a neighbour meets in secret and talks through a crack in the wall.

Pyramus later kills himself thinking himself responsible for Thisbe death. Thisbe find Pyramus dead through this misconception she takes his sword and uses it to commit suicide.

Thisbe has often been referenced in late second millennium works, especially in relation to the wall that separated her and Pyramus. It is thought that Pyramus may have been the basis of Shakespeare's Juliet.