The University of Illinois at Chicago (UIC) is the Chicago campus of the University of Illinois. With 25,000 students, UIC is the largest university in the Chicago area. According to statistics from the UIC web site, 1 in 57 adult Chicagoans, 1 in 10 college graduates in Chicago, and 1 in 6 Illinois physicians are graduates of UIC. UIC has been named as one of the most affordable universities in the United States by US News & World Report and is listed as a college "best buy" in Barron's Best Buys in Education.

UIC was created in 1982 through the consolidation of two University of Illinois campuses, the Medical Center campus, which was established in the 19th century, and the comprehensive Chicago Circle campus established in 1965.