Avianca Flight 410 was a flight that crashed, on March 17 of 1988, at Santander, Colombia. It was a Boeing 727, with the registration #HK-1716. That airplane had flown previously with Pan Am, as #N321PA. All 143 people on board died at this crash.

The crash's investigation pointed out towards a non-crew member who distracted the members of the crew. It has been widely speculated, however, that Colombia's alleged drug kingpin, Pablo Escobar, was involved in the tragedy. Some of the speculations about this theory put Escobar agents bombing the jet-liner.

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