The Battle of Hexham (May 15, 1464) marked the end of significant Lancastrian resistance in the north of England during the early part of the reign of Edward IV.

John Neville, later to be 1st Marquess of Montagu, led a modest force of 3,000-4,000 men, routed the rebel Lancastrians. Most of the rebel leaders were captured and executed, including Henry Beaufort, 2nd Duke of Somerset. Henry VI, however, was kept safely away (having been captured in battle 3 times earlier in his life), and escaped to the north.

With their leadership gone, only a few castles remained in rebel hands. After these fell later in the year, Edward IV was not seriously challenged until the Earl of Warwick switched sides in 1469.