Founded in 1837, DePauw University in Greencastle, Indiana, is a selective private liberal arts college with a 2002 enrollment of 2,339. The school has a Methodist heritage.

The DePauw Tigers compete in the NCAA Division III Southern Collegiate Athletic Conference (SCAC).

Among its faculty is mathematician Underwood Dudley, known for his humorous skeptical books, including Mathematical Cranks and The Trisectors.

DePauw is home to McKim Observatory.

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