Herbsaint is an anise-flavored liqueur from New Orleans. It originated in the 1850s as a cheaper domestic alternative to the French-made absinthe then rapidly gaining in popularity, especially among intellectual and artistic circles. When absinthe was banned in the United States in 1912, it was forced to cease production, but was later reintroduced in a formulation without the banned wormwood, as an American version of pastis. While still produced today, it is now rarely drunk, and is instead used primarily for cooking, most notably as a standard ingredient in the sauce of New Orleans's famous oysters Rockefeller.

The Cresent City Brewhouse in New Orleans serves an excellant example of the the use of 'Herbsaint' in their version of oysters Rockefeller.