Io or IO may stand for:

;Io (mythology): In Greek mythology, Io (pronounced "EYE oh," though "EE oh" is also acceptable) was the daughter of Inachus, a river god. ;Io (moon): moon of Jupiter. ;Io: In Polynesian mythology (including the Maori), the creator god, see Kiho for more information. ;British Indian Ocean Territory: ISO country code