The Human Comedy is a novel by William Saroyan. Homer Macauley is a 14-year-old boy growing up fatherless in the San Joaquin Valley of California during World War II. His oldest brother is off fighting the war, and Homer feels he needs to be the man of the family.

The novel was made into a film in 1943. It stars Mickey Rooney, Frank Morgan, James Craig, Marsha Hunt, Fay Bainter, Ray Collins, Van Johnson and Donna Reed.

The movie was adapted by Howard Estabrook and directed by Clarence Brown.

It won the Academy Award for Best Story and was nominated for Best Actor in a Leading Role (Mickey Rooney), Best Cinematography, Black-and-White, Best Director and Best Picture.