Centuries: 15th century - 16th century - 17th century
- February 24 - Battle of Pavia - Spanish forces under Charles de Lannoy and the Marquis of Pescara defeat the French army and capture King Francis
- Battle of Frankenhausen - Defeat of the rebellious peasants of Germany by the Lords. End of the Peasants War.
- European brought diseases sweep through the Andes, killing thousands including the Inca.
- Reportedly, one of the first adult baptisms was publicly performed in Zurich, Switzerland, in January 1525. Felix Mantz, George Blaurock, and a few others were later persecuted because of these, then rebellious, actions.